49ers-Bills Preview

The San Francisco 49ers and the Buffalo Bills will both be gunning for a victory on Sunday when they meet at Ralph Wilson Stadium. Oddsmakers currently have the Bills listed as 6½-point favorites versus the 49ers, while the game's total is sitting at 43. The 49ers lost to Dallas 35-22 as a 9.5-point underdog last week. The combined score went OVER the posted over/under total (45.5). Shaun Hill threw for 303 yards with two touchdowns and an interception for San Francisco and Isaac Bruce caught eight passes for 125 yards with a TD. The Bills defeated Kansas City 54-31 as a 3-point favorite last week. The combined score went OVER the posted over/under total (42.5). Trent Edwards passed for 273 yards with a pair of touchdown passes and two TD runs for Buffalo, while Marshawn Lynch rushed for 79 yards and a touchdown on 20 carries in the win. Team records: San Francisco: 3-8 SU, 4-7 ATS Buffalo: 6-5 SU, 5-6 ATS San Francisco most recently: When playing in November are 4-6 When playing on turf are 3-7 After being outgained are 1-9 When playing outside the division are 3-7 Buffalo most recently: When playing in November are 5-5 When playing on turf are 5-5 After being outgained are 3-7 When playing outside the division are 6-4 A few trends to consider: The total has gone OVER in 6 of San Francisco's last 7 games San Francisco is 3-9 ATS in its last 12 games on the road San Francisco is 2-6 ATS in its last 8 games San Francisco is 1-4 ATS in its last 5 games when playing Buffalo Buffalo is 4-1 ATS in its last 5 games when playing San Francisco The total has gone OVER in 7 of Buffalo's last 9 games at home Buffalo is 12-6 ATS in its last 18 games at home Buffalo is 2-4 ATS in its last 6 games at home Next up: San Francisco home to NY Jets, Sunday, December 7 Buffalo home to Miami, Sunday, December 7